In an earlier study on the influence of optical defocus on peripheral vision (Rosén et al. acc. for IOVS sept 2010, doi: 10.1167/iovs.10-5623), the two myopes were less sensitive to negative (hyperopic) than to positive (myopic) defocus. This asymmetry was not present for the three emmetropes. Asymmetries in the impact of defocus of different signs are generally interesting for understanding the process of emmetropization. This study therefore investigates the phenomenon in more depth.