Subjective image quality depends not only on optical blur but also on neural factors (Webster et al. 2002). Artal et al. (2004) showed that the eye is adapted to its particular pattern of higher order aberrations, because the subjective blur produced when viewing a scene through one’s own wave aberration was less than that when the wave aberration was rotated. Here, we studied whether this neural adaptation modifies the amount of aberration correction that produces the best subjective image quality. This may have important practical consequences for customized vision correction in eyes with large amounts of higher order aberrations.